Refeyn, a pacesetter in mass photometry expertise, proclaims the launch of its macro mass photometry platform, KaritroMP. This new benchtop instrument marks an evolutionary step past mass photometry, permitting for the characterization of huge viral vectors, together with adenovirus vectors (AdVs) and lentivirus vectors (LVVs). Providing quick, easy, and qualitative evaluation, KaritroMP can inform the R&D of gene and cell therapies, and vaccines.
Not like classical mass photometry expertise, KaritroMP makes use of gentle scattering to measure each the scale and distinction of single particles, permitting for big particles akin to AdVs and LVVs to be characterised throughout two dimensions. Utilizing these measurements, populations of comparable dimension however with completely different plenty might be resolved, enabling the evaluation of the ratio of empty vs full AdV capsids, along with detection of any crude or degraded particles current.
This gives important knowledge on viral vector traits, together with stability, purity, and high quality. Consequently, this method can streamline viral vector course of growth and optimization, permitting customers to simply and shortly evaluate completely different manufacturing and purification strategies, and assess batch-to-batch variation.
Key benefits of the KaritroMP are its pace and ease of use. This benchtop instrument takes simply six minutes to investigate a pattern, and may achieve this autonomously with as much as 13 samples utilizing built-in custom-built software program. The semiautomated workflow requires little pattern, and with fast preparation steps and easy operation, the operational effectivity of analytical processes might be dramatically elevated.
“We’re very excited to announce the launch of the KaritroMP”
Matthias Langhorst, CPO at Refeyn
“With this new expertise, giant viral vectors might be characterised in a brand new method that can also be simple to make use of and quick. We’re trying ahead to seeing our clients understand the advantages of this modern analytical method on the event of their cell and gene therapies and vaccines.”
Matthias Langhorst, CPO at Refeyn
The launch of this new platform exemplifies Refeyn’s dedication to pushing the boundaries of single particle evaluation with its pioneering mass photometry applied sciences – supporting the biopharmaceutical business and facilitating groundbreaking developments. Enabling quick, easy, and reproducible evaluation of single particles together with viral vectors, Refeyn continues to pave the way in which for environment friendly and high-quality analytical workflows, to assist streamline the method growth of novel therapeutics.
To seek out out extra in regards to the KaritroMP and macro mass photometry, please go to: https://www.refeyn.com/karitro-mp.